Japan’s Premier Regenerative Medicine with Tokyo Himawari Clinic
From anti-aging treatments to combating cancer, Tokyo Himawari Clinic partners with Japan Premier Medical Trust (JPMT) to offer personalized, world-class stem cell therapies.
Japan has long been at the forefront of medical advancements and now, through a partnership with some of the country’s most elite clinics, international patients can access cutting-edge treatments previously reserved for a select few. Japan Premier Medical Trust (JPMT) provides a comprehensive concierge service that allows international patients to access advanced treatments, previously available only to a limited number of individuals, through partnerships with top-tier clinics in Japan. This service includes referrals to premier clinics, ranging from medical checkups to advanced regenerative medicine. One such clinic is Tokyo Himawari Clinic.
I had the opportunity to learn more about Tokyo Himawari Clinic, a state-of-the-art facility specializing in stem cell and immune cell therapy, during an exclusive and wide-ranging interview with its CEO and physician, Dr Ryuta Ono.

At Tokyo Himawari Clinic, Founder and CEO Dr Ono is proud to have assembled a highly skilled team of experienced doctors, many of whom are leaders in regenerative medicine and genetic disease research. The clinic even works with Japan’s leading specialist in regenerative medicine, so patients can be rest assured that they will receive top-quality care from experts in the field. Dr Ono works tirelessly to offer patients fully customized regenerative treatments aimed at healing and restoring the body at a cellular level.
What makes Tokyo Himawari Clinic truly innovative is their use of the latest technologies to extract, cultivate and return, both domestically and internationally, an unprecedented number of stem cells—up to 300 million in a single session. Compared to the industry standard of 50-150 million, this vast quantity allows for more robust healing. Dr Ono walked me through the stem cell harvesting process, which begins with a simple biopsy. Fat cells are harvested via a 3-5 mm incision in the abdominal area, a process that sounds invasive but is made to feel anything but due to Dr Ono’s careful consideration for his patients. “We chose this spot for the incision because it is the least painful and least visible,” he explained.

After the cells are harvested, they are then cultured and stored. The clinic houses one of only three latest machines in Japan capable of storing stem cells at -200°C in a fully automated process. This ensures not only the highest quantity of cells for reinfusion but also the highest quality. During treatment, an unprecedented 300 million stem cells are used to rejuvenate tissues with remarkable results. For instance, patients with chronic kidney failure can delay the need for dialysis. Additionally, it was eye-opening to learn during the interview that the approximately 6 billion stem cells present at birth decrease to about 1 billion by age 20, and by age 40, only around 300 million remain—making the large number of stem cells used at TOKYO Himawari Clinic even more impressive.
Cutting-Edge Care with Life-Changing Results
Tokyo Himawari Clinic’s stem cell treatments cater to a broad spectrum of health concerns. The clinic’s services range from anti-aging enhancements such as skin rejuvenation to treatments for more serious health conditions, such as kidney disease and cancer. Cancer patients make up around 20% of the clinic’s clientele, and cutting-edge testing methods are used to identify cancer at the cellular and genetic levels, allowing for more precise, targeted treatments. By analyzing a patient’s blood, Tokyo Himawari Clinic can detect cancer cells, even in their earliest stages, and utilize immune cell therapy to help the body fight the disease naturally.

A typical session at Tokyo Himawari Clinic takes around three hours, with each 60 minutes providing some 100 million stem cells. This efficient and highly effective process means that patients are able to receive the most comprehensive treatment in one visit. “Patients don’t have to be hospitalized,” says Dr Ono. “We’ve had patients come in for treatments and then go golfing on the same day.” For those seeking long-term health benefits without the burden of frequent visits, Tokyo Himawari Clinic offers a remarkable solution.
Dr Ono shared several successful patient stories with me that shed a light on Tokyo Himawari Clinic’s remarkable technology and patient-centered process. One such case involved a 58-year-old man who had been severely injured in a car accident. At the start of treatment, he was unable to raise his arms above shoulder height due to his injuries. After the stem cell therapy, he was able to regain a near full range of motion in his arms, something that Dr Ono attributes to the volume of stem cells that they were able to reintroduce to his body.
Another case involved a 48-year-old woman who sought treatment for skin rejuvenation. Although her reasons for coming to Tokyo Himawari Clinic were cosmetic, she also experienced an unexpected health benefit—her menstrual cycle, which had been irregular, returned to a healthy, monthly pattern after just two treatments. The high concentration of stem cells did more than rejuvenate her skin, they also positively impacted her health.

Invest in Your Health with Tokyo Himawari Clinic
Tokyo Himawari Clinic’s services are not limited to Japanese residents. Dr Ono is motivated by a desire to help people from around the world and foster meaningful connections between Japanese and people from other countries. The clinic welcomes international patients, whether they’re traveling to Japan for a brief visit or living in the country long-term. International patients can be sure that they are receiving the same high standard of care as domestic patients, and the clinic’s interpreters help eliminate language barriers to make sure patients feel fully supported throughout their treatment.
With a commitment to excellence and innovation, Tokyo Himawari Clinic offers more than just cutting-edge regenerative treatments—it offers hope and healing for those seeking to improve their quality of life. Whether you are looking to enhance your youthful appearance, combat a serious illness or simply invest in your future health, Tokyo Himawari Clinic’s stem cell therapies provide a safe and effective solution. Partnering with Japan Premier Medical Trust, this clinic is setting a new standard in medical care, attracting patients from around the globe who demand the best.

For any inquiries, please contact Yoshifumi Abe of Japan Premier Medical Trust at abe@j-pmt.com or call +81-80-5484-6850 (English or Japanese).